Status:
RECRUITING
Long-term Longitudinal Imaging of Presynaptic Terminals in PD
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Conditions:
Parkinson Disease
Eligibility:
All Genders
30+ years
Phase:
NA
Brief Summary
AIM: To investigate whether SV2A loss spreads from brainstem to cerebral cortex with progression of Parkinson's disease (PD) and to determine whether longitudinal cortical SV2A loss correlates with co...
Eligibility Criteria
Inclusion
- Participation in study S61477 (NCT04243304)
Exclusion
- Neuropsychiatric diseases (unrelated to PD for PD patients)
- Major internal medical diseases
- History of alcohol or drug abuse
- Relevant abnormalities on MR brain
- Contraindications for MR
- Pregnancy or breastfeeding
- Previous participation in other research studies involving ionizing radiation with \> 1 mSv over past 12 months.
Key Trial Info
Start Date :
July 16 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2027
Estimated Enrollment :
35 Patients enrolled
Trial Details
Trial ID
NCT06875765
Start Date
July 16 2025
End Date
December 1 2027
Last Update
July 29 2025
Active Locations (1)
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1
UZ Leuven
Leuven, Belgium, 3000