Status:

RECRUITING

Staged Kidney Transplantation During Combined Heart/Kidney Transplantation

Lead Sponsor:

Cedars-Sinai Medical Center

Conditions:

Heart Failure

Chronic Kidney Disease

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The primary purpose of this study is to evaluate the safety and efficacy of ex vivo machine perfusion with staged implantation of kidney allografts during combined heart/kidney transplantation.

Detailed Description

Combined heart and kidney transplantation (H/KTx) is the treatment of choice for patients with concomitant heart failure and chronic- or end-stage kidney disease. H/KTx presents a logistical challenge...

Eligibility Criteria

Inclusion

  • Adult patients (18 years or older) undergoing combined heart and kidney transplantation at Cedars-Sinai Medical Center.

Exclusion

  • Patients who undergo simultaneous heart/kidney transplantation in a single operative event due to medical necessity will be excluded.
  • Patients with medical records flagged as "break-the-glass" or "research opt-out" within the center's electronic health record.

Key Trial Info

Start Date :

April 7 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 28 2035

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06877169

Start Date

April 7 2025

End Date

February 28 2035

Last Update

June 3 2025

Active Locations (1)

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1

Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048