Status:
NOT_YET_RECRUITING
Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease
Lead Sponsor:
University of Edinburgh
Collaborating Sponsors:
NHS Lothian
Conditions:
Covert Cerebrovascular Disease
Eligibility:
All Genders
65+ years
Brief Summary
The purpose of the DISCOVER study is to pilot acceptable approaches to people with covert cerebrovascular disease (CCD) and their follow-up. This is the first step in designing efficient randomised tr...
Detailed Description
DISCOVER is a prospective cohort involving individuals with covert cerebrovascular disease (CCD) in NHS Lothian. Participants will be recruited through electronic health records and clinician collabor...
Eligibility Criteria
Inclusion
- People who, at the time the letter is prepared or are identified by a clinician
- Age ≥ 65 years
- Have no known history of:
- Stroke or TIA
- Dementia
- Parkinson's disease
- Multiple sclerosis
- Metastatic cancer (or non-meningioma brain tumour).
- A CT or MRI scan report ≤5 years before study start date with of one or more of:
- Cerebral small vessel disease
- Deep old ischaemic stroke
- Cortical old ischaemic stroke
Exclusion
- Text of brain scan report unreadable
- Do not consent to take part in study procedures
- Unable to consent
- Unable to communicate by email, letter or telephone through language, speech disability or lack of address
- Unlikely to survive one year past enrolment in judgement of the study investigator
Key Trial Info
Start Date :
December 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2027
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06878430
Start Date
December 1 2025
End Date
June 1 2027
Last Update
August 11 2025
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