Status:

ACTIVE_NOT_RECRUITING

Web-Based Exercise for Neuropathy and Quality of Life in Breast Cancer

Lead Sponsor:

Bilecik Seyh Edebali Universitesi

Conditions:

Chemotherapy-Induced Peripheral Neuropathy (CIPN)

Breast Cancer

Eligibility:

FEMALE

18-75 years

Phase:

NA

Brief Summary

Chemotherapy is a widely used treatment method for cancer patients. However, various side effects may occur depending on the drug used, treatment duration, and dosage. One of these side effects is che...

Detailed Description

Breast cancer is the most common type of cancer among women worldwide and in our country, ranking second among the leading causes of cancer-related deaths. Chemotherapy drugs are among the most widely...

Eligibility Criteria

Inclusion

  • Able to understand and speak Turkish,
  • Over 18 years of age,
  • Receiving taxane-based chemotherapy in daytime chemotherapy units,
  • Reporting at least one neuropathy symptom according to CIPNAT,
  • Diagnosed with stage II-III breast cancer,
  • Receiving a planned weekly taxane-based chemotherapy infusion dose (70-99 mg/m², 100-129 mg/m², 130-159 mg/m², 160 mg/m² and above) and completing 8 treatment cycles,
  • Having internet access,
  • No history of deep vein thrombosis,
  • Not using anticoagulant medication,
  • Willing to participate in the study.

Exclusion

  • Younger than 18 years or older than 75 years,
  • Having central nervous system disorders affecting movement, balance, sensation, or coordination,
  • Presence of any skin infection, scar tissue, inflammation, or incision on the hands or ankles,
  • Diagnosed with a proven cardiac condition or using medication for cardiac issues,
  • Pregnant women or those in the postpartum period,
  • History of polyneuropathy before chemotherapy,
  • Cognitive impairment,
  • Presence of metal implants in the exposure area,
  • History of any other malignancy,
  • Undergoing mastectomy.
  • Withdrawal Criteria
  • Patients meeting the following conditions will be withdrawn from the study:
  • Patients whose taxane treatment protocol is changed,
  • Patients who wish to withdraw from the study,
  • Patients with a pulse rate above 100 bpm,
  • Patients receiving fewer than four weekly chemotherapy applications,
  • Women without internet access or those who do not visit the website at least five times for four hours throughout the follow-up period.

Key Trial Info

Start Date :

May 28 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 10 2025

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06879678

Start Date

May 28 2025

End Date

October 10 2025

Last Update

May 31 2025

Active Locations (1)

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1

Gulhane Education and Research Hospital, Ankara, 06010

Ankara, Turkey (Türkiye), 06010