Status:
RECRUITING
Cross-section Band Ligation Versus Stepladder Band Ligation of Esophageal Varices
Lead Sponsor:
Tanta University
Conditions:
Esophageal Varices
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this randomized controlled trial is to evaluate the cross-section band ligation technique versus the stepladder band ligation technique in esophageal varices prophylaxis. Researchers will...
Eligibility Criteria
Inclusion
- Aged \>18 years.
- Cirrhotic patients.
- Endoscopic evidence of medium/large-sized esophageal varices.
Exclusion
- History of variceal bleeding or previous primary prevention of varices.
- Portal vein thrombosis or previous porto-systemic shunts as TIPS.
- Patients on drugs affecting portal pressure (beta blockers, nitrates).
- Advanced cardiovascular disease including acute myocardial infarction, atrio-ventricular block, congestive heart failure, chronic peripheral ischemia, and severe bradycardia.
- Patients with severe respiratory diseases (COPD, bronchial asthma).
- Uncontrolled diabetes mellitus.
- Renal impairment.
- Hepatocellular carcinoma.
- Allergy to carvedilol.
- Pregnancy or lactation.
Key Trial Info
Start Date :
December 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 30 2025
Estimated Enrollment :
320 Patients enrolled
Trial Details
Trial ID
NCT06881082
Start Date
December 1 2024
End Date
December 30 2025
Last Update
March 18 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tanta University Hospitals
Tanta, Gharbyea, Egypt, 31516