Status:

NOT_YET_RECRUITING

SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.

Lead Sponsor:

The University of Queensland

Collaborating Sponsors:

Brooke Army Medical Center

United States Department of Defense

Conditions:

Persistent Post-concussive Symptoms

Post Traumatic Headache

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

This is a prospective randomized controlled trial comparing two different physical therapy approaches to the treatment of posttraumatic headache with autonomic symptoms. AIM 1: To establish the effica...

Detailed Description

Persistent post traumatic headache (PPTH) is a significant problem for the US military affecting up to 33% of service members with a history of mild traumatic brain injury (mTBI) and treatment is usua...

Eligibility Criteria

Inclusion

  • Persistent Post-traumatic headache (PPTH) duration =or \> 4 weeks.
  • No self-reported improvement in headache pattern in the past 3 weeks. (Patients will be asked to determine whether the usual pattern of their headaches has changed for the better over the last 3 weeks.
  • Compass-31 score \> 21 to select patients who have evidence of ANS dysfunction which SPINEPASS aims to address.
  • Headache Impact Test (HIT6) =\>50 to capture headache-related disability of "some impact" or more.
  • Headache worst intensity \>3/10 on a numerical rating scale (NRS), at least once per week.

Exclusion

  • Contraindications for spinal or graded general exercise.
  • Contraindications to spinal manual therapy at or below C5-6 level
  • Cognitive impairment/ language barriers affecting ability to participate.
  • Redeployment/relocation or retirement planned within the next 6 months to reduce the chances of dropouts to treatment and follow-up.
  • Rating self-confidence to manage (eliminate and or lower) headaches without abortive medication at baseline of 30% or greater.
  • Inability to attend up to 12 in-person treatment sessions for 4 months.
  • Unwilling to limit commencement of other management for PPTH during the trial period.
  • Botox for headache management within the last 8 weeks or during the trial.

Key Trial Info

Start Date :

May 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 30 2028

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT06882239

Start Date

May 1 2025

End Date

September 30 2028

Last Update

March 18 2025

Active Locations (1)

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Brook Army Medical Center

San Antonio, Texas, United States, 78234