Status:
COMPLETED
Neural Mechanisms of Dialectical Behavioral Therapy in Patients with Borderline Personality Disorder
Lead Sponsor:
Masarykova Univerzita
Collaborating Sponsors:
Brno University Hospital
Masaryk University
Conditions:
Borderline Personality Disorder
Eligibility:
All Genders
16+ years
Phase:
NA
Brief Summary
This research examines the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD).
Detailed Description
This project aims to evaluate the behavioral and neural mechanisms of dialectical behavior therapy (DBT) effect in patients with borderline personality disorder (BPD). The project includes three subje...
Eligibility Criteria
Inclusion
- BPD-DBT group:
- diagnosis of borderline personality disorder according to Diagnostic and Statistical Manual 5th Edition (DSM-5) criteria (rated by Structured Clinical Interview for DSM-5 for Personality Disorders, BPD section)
- minimum age 16, informed consent of the patient
- informed consent of patient's legal representative in case of patients under age 18
- more than one self-injury incident and/or suicidal attempt in the past six months
Exclusion
- neurological disorder
- comorbid affective disorder or schizophrenia-related disorder
- intelligence quotient\<70
- contraindications for MRI measurement
- pregnancy
- body mass index under 15
- BPD-C group:
- Inclusion Criteria:
- diagnosis of borderline personality disorder according to Diagnostic and Statistical Manual 5th Edition (DSM-5) criteria (rated by Structured Clinical Interview for DSM-5 for Personality Disorders, BPD section)
- minimum age 16, informed consent of the patient
- informed consent of patient's legal representative in case of patients under age 18
- more than one self-injury incident and/or suicidal attempt in the past six months
Key Trial Info
Start Date :
August 27 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 15 2023
Estimated Enrollment :
106 Patients enrolled
Trial Details
Trial ID
NCT06882330
Start Date
August 27 2020
End Date
August 15 2023
Last Update
March 18 2025
Active Locations (1)
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1
University Hospital Brno and Faculty of Medicine, Masaryk University
Brno, Czech Republic, Czechia, 62500