Status:
NOT_YET_RECRUITING
Predictors of Spontaneous Bacterial Peritonitis Among Patients with Cirrhosis
Lead Sponsor:
Assiut University
Conditions:
Cirrhosis
Eligibility:
All Genders
18-70 years
Brief Summary
Prevalence of spontaneous bacterial peritonitis (SBP) varies from approximately 4% among asymptomatic patients to 30% among those hospitalized \[1, 2\].Previous studies explored the role of several bi...
Eligibility Criteria
Inclusion
- include cirrhotic patients with Moderate-marked ascites, as determined by abdominal ultrasonography (US). SBP will be diagnosed based on detection of polymorph nuclear leukocytes (PMNs) \>250 cells/mcL and/or white blood cells (WBCs) \>500 cells/mcL by ascitic fluid examination.
Exclusion
- 1- Pediatric patients (less than 18 years old) and patients older than 70 years Pregnant patients .
- 2-Etiology of ascites other than cirrhosis. 3-Receiving antibiotics and/or prophylaxis four weeks before admission. 4- Concurrent bacterial infection other than SBP. 5- Abdominal surgery 12 weeks before admission 6-Patients with neoplastic or hematological disease. 7- Patients who received bone marrow transplantation, chemotherapy, or radiotherapy four weeks before admission.
- 8- Conditions associated with increased MPV such as systemic hypertension, diabetes mellitus, dyslipidemia, peripheral vascular disease, thyroid disease, and therapy four weeks before admission with antiplatelet agents and nonsteroidal anti-inflammatory drugs
Key Trial Info
Start Date :
April 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2026
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT06884306
Start Date
April 1 2025
End Date
July 1 2026
Last Update
March 19 2025
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