Status:
NOT_YET_RECRUITING
Detection of Internal Tremors by Oscillometry in Parkinson's Patient
Lead Sponsor:
University Hospital, Toulouse
Collaborating Sponsors:
Fondation de l'Avenir
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The goal of the present study is to objectively access the presence of an Internal Tremor in Parkinson's disease. Inertial sensors will be used to detect the presence of a rhythmic oscillation of 3-4 ...
Detailed Description
The interest in finding prodromal symptoms in Parkinson's disease has been growing. Internal tremor, felt subjectively by the patients, have been reported in some studies as being present on the Prodr...
Eligibility Criteria
Inclusion
- (For the experimental group)
- Patient with idiopathic parkinson's disease
- Mini Mental State Evaluation score above or equal to 25
- Hoehn and Yahr scale score of ≤3 in the OFF phase, with postural stability allowing the patient to stand unaided for 1 minute.
- Able to walk unassisted
- No major osteoarticular issues
- Presence of another neurological condition that may affect gait
- Willing to undergo accelerometry in the OFF state
- (For the control group)
- Healthy volunteer subjects matched for age (+/- 5 years) and sex
- Mini Mental State Evaluation score above or equal to 25
Exclusion
- (For the experimental group)
- Patients with an atypical parkinsonian syndrome
- Patients unable to walk or stand for more than one minute in the off state
- Parkinson's patients treated with deep brain stimulation, apomorphine pump, or duodopa intestinal infusion, and foslevodopa
- Pregnant patients
- (For the control group)
- Participants with significant gait impairment (osteoarticular disorder)
- Those with a neurological disease that, in the investigator's judgment, may interfere with the study's outcome measure
- Participants with a clinical tremor that may interfere with the measurement of the primary outcome (e.g., essential tremor, thyroid disease, or tremors induced by medication)
- Pregnant participants
Key Trial Info
Start Date :
March 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT06885541
Start Date
March 1 2025
End Date
December 1 2025
Last Update
March 20 2025
Active Locations (1)
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1
Purpan Hospital
Toulouse, Occitanie, France, 31059