Status:
COMPLETED
Periapical Bleeding Versus PRF Techniques in Regenerative Endodontic Therapy: A Randomized Controlled Trial
Lead Sponsor:
Saglik Bilimleri Universitesi
Conditions:
Necrotic Pulp
Regenerative Endodontic Procedures
Eligibility:
All Genders
14-65 years
Phase:
NA
Brief Summary
This study investigates a biological approach that allows infected and necrotic teeth to heal themselves instead of being treated with traditional root canal therapy. Traditional root canal treatment ...
Detailed Description
This study investigates the effectiveness of regenerative endodontic procedures in the treatment of necrotic and infected teeth. Traditional root canal treatment involves the complete removal of infec...
Eligibility Criteria
Inclusion
- Single-rooted teeth with mature teeth with necrotic pulp requiring endodontic treatment, and a periapical lesion (Periapical Index Score (PAI) ≥3).
- Individuals without systemic diseases, not using antibiotics, corticosteroids, antidiabetic, or antihypertensive medications, and not pregnant.
- Patients without acute pain.
- Patients without extraoral swelling, sinus tract, or acute apical abscess.
- Individuals willing to participate and able to attend follow-up sessions regularly.
Exclusion
- Teeth with internal or external root resorption or vertical root fractures.
- Immature teeth.
- Individuals outside the age range of 14-65 years.
- Patients with complicated systemic diseases or those using antibiotics, corticosteroids, antidiabetic, or antihypertensive medications.
- Patients with acute pain, those who have taken analgesic medication in the last 24 hours, or those who have used antibiotics within two weeks before treatment.
- Patients who are unlikely to attend follow-up sessions.
Key Trial Info
Start Date :
February 3 2024
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 24 2025
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT06886438
Start Date
February 3 2024
End Date
January 24 2025
Last Update
March 20 2025
Active Locations (1)
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1
Gulhane Faculty of Dentistry, University of Health Sciences
Ankara, Etlik, Turkey (Türkiye), 06010