Status:

COMPLETED

Immediate Effect of Mobilization with Movement on Squat Self-reported Functional Ability, Pain Intensity, and Pain-free Range of Motion in People with Knee Osteoarthritis

Lead Sponsor:

Escola Superior de Tecnologia da Saúde do Porto

Conditions:

Knee Osteoarthritis (Knee OA)

Eligibility:

All Genders

45+ years

Phase:

NA

Brief Summary

Mobilization with movement (MWM) appears to reduce pain, improve knee range of motion, and enhance physical functioning in individuals with knee osteoarthritis (KOA). However, it remains unclear wheth...

Eligibility Criteria

Inclusion

  • male or female;
  • aged over 45 years;
  • clinically diagnosed with symptomatic unilateral KOA, classified as grade 1-3 according to the Kellgren and Lawrence system;
  • fulfilled the classification criteria of the American College of Rheumatology for KOA;
  • reported frequent episodes of pain in the knee joint during sit-to-stand movements for at least 3 months.

Exclusion

  • had KOA secondary to rheumatoid arthritis and other inflammatory and autoimmune conditions;
  • reported lumbar pain radiating to the knee or lumbar pain as the primary complaint;
  • had a history of knee or lower limb surgery;
  • had a systemic or local infection;
  • had received an intra-articular corticosteroid or hyaluronic acid injection within the past 6 months;
  • reported current or past (within 4 weeks) oral corticosteroid use;
  • had any condition in the lower limbs that would prevent performing the deep squat test;
  • had clinical conditions in which manual therapy is generally contraindicated (such as fracture, osteoporosis, instability, infectious arthritis, tumors, joint ankylosis, acute inflammatory disorders, or lack of a diagnosed joint lesion).

Key Trial Info

Start Date :

May 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 31 2023

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT06887868

Start Date

May 1 2022

End Date

July 31 2023

Last Update

March 24 2025

Active Locations (1)

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E2S | P.PORTO - Escola Superior de Saúde do Politécnico do Porto

Porto, Porto District, Portugal, 4200-072