Status:
ENROLLING_BY_INVITATION
Tissue Microdialysis Monitoring of Liver Grafts
Lead Sponsor:
University Medical Centre Ljubljana
Conditions:
Liver Transplantation
Liver Graft Dysfunction
Eligibility:
All Genders
18-65 years
Brief Summary
This study will investigate the dynamics of metabolic molecules sampled from human liver grafts during the early postoperative period using tissue microdialysis. The obtained tissue samples will be co...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Adult patients aged between 18 and 65 years.
- Liver transplant candidates on the Slovenian liver transplant waiting list, matched with an available liver graft through the Eurotransplant system, and scheduled for the surgical procedure.
- Signed informed consent to participate in the microdialysis sampling research project, including consent to share the obtained samples with other research studies
- Exclusion criteria:
- Patients under 18 or over 65 years of age.
- Refusal to participate in the study.
- Verbal withdrawal of consent at any point during the study, even if informed consent has been previously signed.
- Surgical contraindications preventing the insertion of a microdialysis catheter into the liver graft during the procedure.
- Surgical revision within 48 hours post-transplantation resulting in liver graft loss and removal.
- History of allergic reactions to radiographic contrast media.
- Death during the liver transplant procedure.
Exclusion
Key Trial Info
Start Date :
May 11 2022
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT06890234
Start Date
May 11 2022
End Date
December 31 2025
Last Update
March 21 2025
Active Locations (1)
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1
University Medical Centre Ljubljana
Ljubljana, Slovenia, Slovenia, 1000