Status:

RECRUITING

Timing of Anticoagulant Administration During Radial Access Percutaneous Coronary Intervention: the HERA-PCI Study (Heparin Early for Radial Access Percutaneous Coronary Intervention)

Lead Sponsor:

University Hospital, Strasbourg, France

Conditions:

Coronary Angiography

Percutaneous Coronary Intervention

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

While the reduced hemorrhagic risk of radial access for percutaneous coronary intervention compared to femoral access is well-established, its main complication remains radial artery occlusion, which ...

Detailed Description

Prevention of radial occlusion relies on optimal hemostasis and anticoagulation. Previous studies have demonstrated a decrease incidence of radial artery occlusion through hemostasis at the puncture s...

Eligibility Criteria

Inclusion

  • Patients having 18 years old or older, regardless of gender, undergoing percutaneous radial coronary intervention
  • Subject affiliated to a social protection health insurance
  • Subject able to understand the objectives and risks of the research and to provide dated and signed consent
  • Subject who has been informed of the results of the preliminary medical examination

Exclusion

  • Contraindication to the use of heparin (history of heparin-induced thrombocytopenia)
  • Very high bleeding risk defined by recent bleeding (\<6 months) of type 3 of the BARC classification
  • Subject in an exclusion period (determined by a previous or ongoing study)
  • Inability to give the subject enlightened information (subject in an emergency situation, difficulties in understanding the subject, etc.)
  • Subject under safeguard of justice
  • Subject under guardianship or curatorship
  • Pregnancy
  • Breastfeeding
  • Patient on anticoagulant treatment: anti-vitamin K, direct oral anticoagulants (DOACs).

Key Trial Info

Start Date :

June 5 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 1 2026

Estimated Enrollment :

550 Patients enrolled

Trial Details

Trial ID

NCT06890312

Start Date

June 5 2025

End Date

January 1 2026

Last Update

September 5 2025

Active Locations (1)

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Hôpitaux Universitaires de Strasbourg

Strasbourg, Bas-Rhin, France, 67091