Status:

ACTIVE_NOT_RECRUITING

Feasibility of Day-surgery Management for Patients Undergoing Robotic Radical Prostatectomy: a Randomized Trial

Lead Sponsor:

Regina Elena Cancer Institute

Conditions:

Prostate Cancer

Eligibility:

MALE

18-75 years

Phase:

NA

Brief Summary

To compare the day-surgery approach versus routine management in patients undergoing robotic radical prostatectomy, aimed at evaluating the feasibility of a one-day hospitalization regimen for robotic...

Detailed Description

The clinical study is aimed at evaluating the compliance of patients, candidates for robot-assisted radical prostatectomy for prostate cancer, to be enrolled in an RCT that provides for assignment to ...

Eligibility Criteria

Inclusion

  • patients with localized prostate adenocarcinoma at low-intermediate risk (EAU Risk classification);
  • patients aged \>= 18 years;
  • patients with an indication to undergo robotic radical prostatectomy without lymphadenectomy according to the EAU guidelines;
  • patients who agree to undergo robotic radical prostatectomy without lymphadenectomy according to the EAU guidelines by signing a written informed consent;
  • patients eligible for robotic radical prostatectomy without lymphadenectomy and in the absence of contraindications to undergo the procedure;
  • patient's ability to understand and willingness to sign a written informed consent indicating that he has understood the purpose and methods of conducting the study and is interested in participating.;
  • patients able to follow the indications specified in the study protocol;
  • patients domiciled (even temporarily) \< 150 km away from the institution where the procedure will be performed;
  • patients domiciled (even temporarily) \< 60 minutes by car from a reference Emergency and Acceptance Department (DEA).

Exclusion

  • patients \> 75 years of age;
  • ASA \> 2;
  • second simultaneous surgery;
  • prostate volume \> 80 cc estimated on preoperative imaging (transrectal ultrasound or magnetic resonance imaging);
  • patients receiving anticoagulants or oral antiplatelet drugs;
  • other concomitant tumors undergoing treatment;
  • previous pelvic radiotherapy;
  • previous surgery for benign prostatic hypertrophy;
  • patients lacking the digital literacy required to take advantage of telemedicine intervention;
  • patients who cannot benefit from at least one caregiver;
  • patients not suitable for a day-surgery approach based on the clinical evaluation of the operating surgeons and anesthetists.

Key Trial Info

Start Date :

October 23 2024

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 23 2027

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT06891664

Start Date

October 23 2024

End Date

May 23 2027

Last Update

March 24 2025

Active Locations (1)

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"Regina Elena" National Cancer Institute

Rome, Italy, 00144