Status:
COMPLETED
Impact of Home-Based Aerobic and Resistance Training in Chronic Liver Disease: a Randomized Control Trial
Lead Sponsor:
Hacettepe University
Conditions:
Chronic Liver Disease and Cirrhosis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to evaluate whether home-based exercise interventions, including aerobic exercise (AE) and a combination of aerobic and resistance exercise (ARE), can improve physic...
Detailed Description
This randomized controlled trial was designed to evaluate the effects of an 8-week home-based exercise program on physical and health-related outcomes in patients with Chronic Liver Disease (CLD). The...
Eligibility Criteria
Inclusion
- Being followed up for chronic liver disease or listed on the liver transplant waiting list at the Hacettepe University Department of Internal Medicine, Division of Gastroenterology.
- Owning and being able to use a smartphone.
- Aged between 18 and 70 years.
- Receiving primary prophylactic treatment for gastroesophageal varices.
- Willingness to participate in the study.
Exclusion
- Inability to own or use a smartphone.
- Participation in an exercise training program within the last year.
- Previous liver transplantation.
- High-risk varices without beta-blocker treatment.
- Presence of persistent hepatic encephalopathy.
- Hepatic hydrothorax.
- Pulmonary vascular complications of portal hypertension.
- Chronic renal failure requiring dialysis.
- Hemoglobin level below 10 g/dL.
- Creatinine level above 2 mg/dL.
- Human Immunodeficiency Virus (HIV) infection.
- Presence of hepatocellular carcinoma (HCC).
- Recent acute myocardial infarction.
- Uncontrolled arrhythmias causing symptomatic hemodynamic instability.
- Contraindications to maximal exercise testing.
- Physical or orthopedic conditions preventing home-based exercise training.
- Lack of willingness to participate in the study.
Key Trial Info
Start Date :
September 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 16 2024
Estimated Enrollment :
39 Patients enrolled
Trial Details
Trial ID
NCT06892366
Start Date
September 20 2020
End Date
June 16 2024
Last Update
March 24 2025
Active Locations (1)
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1
Hacettepe University Faculty of Physical Therapy and Rehabilitation
Ankara, Altındağ, Turkey (Türkiye), 06100