Status:
RECRUITING
Effect of an Intervention Program of Adapted Physical Activity Combined With Compensatory Nutrition in Patients With Constitutional Thinness
Lead Sponsor:
Centre Hospitalier Universitaire de Saint Etienne
Collaborating Sponsors:
Laboratoire Interuniversitaire de Biologie de la Motricité
Target Tape
Conditions:
Constitutional Thinness
Eligibility:
FEMALE
18-50 years
Phase:
NA
Brief Summary
Constitutional Thinness (CT) is a form of stable thinness without malnutrition but with resistance to weight gain, affecting approximately 1% of the general population. The clinical consequences are n...
Eligibility Criteria
Inclusion
- Gender: Female
- BMI: ≤ 18.5 kg/m²
- Weight Stability: Stable weight for at least 3 months
- Age: 18 to 50 years old at the inclusion visit
- Diagnosed with Constitutional thinness
Exclusion
- Pregnancy, Parturition, or Lactation
- Legal Restrictions: Individuals deprived of liberty, involuntarily hospitalized, or hospitalized for reasons other than research purposes, adults under legal protection (guardianship or curatorship) or unable to provide consent
- Eating Disorders: Individuals with eating disorders (DSM IV and 5 criteria)
- Excessive Alcohol Consumption: Consumption exceeding the equivalent of 10 glasses of wine per week
- Severe Progressive Conditions: Progressive severe conditions (e.g., diabetes)
- Intense Physical Activity: Individuals engaging in intense physical activity (\> 3 sessions per week)
- Heavy Smoking: Significant smoking (\>10 cigarettes per day)
- Psychiatric Conditions: Presence of depressive or psychiatric conditions requiring antidepressant or psychotropic treatment
- Medical or Surgical History: Medical or surgical history deemed incompatible with the study by the investigator
- MRI Contraindication: Individuals with contraindications to MRI will not undergo spectro-MRI analyses
Key Trial Info
Start Date :
July 7 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
62 Patients enrolled
Trial Details
Trial ID
NCT06894043
Start Date
July 7 2025
End Date
June 1 2026
Last Update
October 7 2025
Active Locations (1)
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1
CHU de Saint-Etienne
Saint-Etienne, France, France, 42055