Status:
ACTIVE_NOT_RECRUITING
The Effect of an Antioxidant Gel Compared to Chlorhexidine Gel During the Soft Tissue Healing Process: A Randomized Controlled Clinical Trial
Lead Sponsor:
Kuwait University
Conditions:
Periodontal Diseases
Eligibility:
All Genders
18-60 years
Phase:
PHASE4
Brief Summary
This study aims to evaluate the comparative impact of chlorhexidine and antioxidant gel on postoperative biomarkers following SRP. By examining biomarkers related to inflammation, oxidative stress, an...
Detailed Description
Background Periodontitis is characterised by inflammation that results in the loss of periodontal attachment. Scaling and root planing (SRP) is a fundamental non-surgical treatment for periodontitis,...
Eligibility Criteria
Inclusion
- Patients with Stage 3 or 4 periodontitis would be invited to participate in this study.
- The following parameters will be used for the diagnosis of periodontitis: (a) presence of bleeding on gentle probing; (b)probing depth (PD) \>6mm; and (c) marginal bone loss (MBL) of at least 3.
Exclusion
- Patients will be excluded from the study if they present with gingivitis alone, are currently using oral contraceptives, have systemic conditions such as diabetes or cancer, or are smokers (including those who quit within the past 6 months).
- Recent antibiotic use within the last 3 months, NSAID or bisphosphonate use within the last 90 days, and any use of chlorhexidine in the past 6 months.
Key Trial Info
Start Date :
November 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT06894667
Start Date
November 1 2024
End Date
December 1 2025
Last Update
March 25 2025
Active Locations (1)
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1
Faculty of Dentistry
Kuwait City, Kuwait, 13110