Status:

NOT_YET_RECRUITING

Effect of Ilex Paraguariensis Harvest Time and Consumption Method of Processed Yerba Mate on the Lipid Profile

Lead Sponsor:

Universidad Nacional de Caaguazu

Collaborating Sponsors:

Hospital Nacional de Itaugua, MSPyBS, Paraguay)

Instituto Nacional de Salud, Paraguay

Conditions:

Lipid Metabolism Disorders

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Introduction: This project studies the impact of Ilex paraguariensis harvest time, commonly known as yerba mate, and its consumption mode (mate, tereré, and mate/terere) on the lipid profile of consum...

Eligibility Criteria

Inclusion

  • Individuals of both sexes, between 18 and 60 years of age, residing in the country, who consume prepared yerba mate.
  • Consumers of mate or tereré and mate/terere who agree to consume the yerba mate samples provided by the research team, which will be masked from laboratory analysis.
  • Two weeks of abstinence from consuming prepared yerba mate, either as mate or tereré, prior to randomization for the trial.
  • Consume exclusively prepared yerba mate in the prescribed manner (quantity of yerba, frequency of consumption, and sips), either in its mate or tereré form independently, and for those who consume both forms daily.
  • Do not change the yerba mate consumer's usual diet or regular physical activity during the trial period.
  • Agree to know the laboratory results of the lipid profile only at the end of the trial (180 days after the start).

Exclusion

  • Individuals receiving lipid-lowering treatment at the start of the trial.
  • Consuming any other type of yerba mate not provided by the principal investigator.
  • Individuals requiring vitamins as a nutritional supplement.
  • Individuals taking thermogenic supplements.
  • Individuals consuming cooked mate.
  • Addiction to medicinal plants or herbs, both mate and tereré.
  • Individuals with a personal history of coronary artery disease.

Key Trial Info

Start Date :

February 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2026

Estimated Enrollment :

198 Patients enrolled

Trial Details

Trial ID

NCT06896175

Start Date

February 1 2026

End Date

October 1 2026

Last Update

March 30 2025

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