Status:
RECRUITING
Analysis of Coronary Reactivity Testing With and Without Intracoronary Nitrate Testing
Lead Sponsor:
Baylor Research Institute
Conditions:
ANOCA - Angina With Non-obstructive Coronary Arteries
INOCA (Ischemia With Non Obstructive Coronary Artery Disease)
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This single-arm, multi-center, prospective study will assess the coronary flow reserve (CFR), index of microcirculatory resistance (IMR), and determinants thereof (transit time, Pa, Pd) in patients be...
Detailed Description
This will be a single arm, multi-center, prospective interventional study. We will approach, consent, and enroll patients referred to the cardiac catheterization laboratory for coronary angiography fo...
Eligibility Criteria
Inclusion
- Aged 18 or older
- Patient being evaluated for ANOCA or INOCA
- Clinical suspicion for angina
- Patient should be able to comply with the protocol.
- Provide written informed consent before study participation.
Exclusion
- Existing coronary artery disease
- Previous percutaneous interventions within the coronaries
- Current use (within 48 hours) of long-acting nitrate therapies
- Current use (within 48 hours) of PDE-5 inhibitors (sildenafil, tadalafil)
- Any other condition or co-morbidity which, in the opinion of the investigator or operator, may pose a significant hazard to the subject if he or she is enrolled in the study.
- Children below 18 years, prisoners, pregnant people and patients who are unable to provide consent are excluded.
Key Trial Info
Start Date :
May 21 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT06896903
Start Date
May 21 2025
End Date
June 1 2026
Last Update
June 4 2025
Active Locations (1)
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1
Baylor Scott & White The Heart Hospital - Plano
Plano, Texas, United States, 75093