Status:
ACTIVE_NOT_RECRUITING
Consistency of Response With Rimegepant in Acute Treatment of Migraine
Lead Sponsor:
Pfizer
Conditions:
Migraine
Eligibility:
All Genders
18+ years
Brief Summary
This is a non-interventional, prospective study that will enroll participants with migraine in the United Kingdom currently in use of rimegepant to acutely treat migraine attacks. Participants will be...
Detailed Description
This is a prospective observational, real-world cohort study of the patient-reported consistency of response to rimegepant in acute treatment of migraine. Longitudinal data capture will allow the dete...
Eligibility Criteria
Inclusion
- Inclusion criteria
- UK resident.
- At least 18 years of age.
- Migraine diagnosis confirmed by healthcare professional.
- Current prescription of rimegepant for acute treatment of migraine.
- Experienced at least 4 migraine attacks per month prior to study enrolment.
- In the case of participants receiving preventive migraine treatment:
- For oral preventives, the treatment must be "stable" i.e., final dosing regimen has been found.
- For migraine preventives administered monthly, the participant must have had their most recent treatment within the 3 weeks prior to study enrolment.
- For migraine preventives administered quarterly, the participant must have had their most recent treatment within the 2 months prior to study enrolment.
- If the last treatment is not within the stipulated period, participants will be asked to provide the date of the next scheduled treatment, after which the participant may be invited back to enrol into the study.
- Evidence of a personally signed (or acknowledged if obtained electronically or online) and dated informed consent document indicating that the participant has been informed of all pertinent aspects of the study.
- Exclusion criteria
- Current use of rimegepant as a preventive migraine medication.
- Current diagnosis of any of the following conditions:
- new daily persistent headache
- chronic daily headache
- cluster headache
- post-traumatic headache
- hemicrania continua
- major depression
- pain syndromes other than migraine (e.g. fibromyalgia)
- psychiatric conditions (e.g., schizophrenia)
- dementia
- significant neurological disorders other than migraine.
- Current prescription of any of the following medications:
- Strong inhibitors of CYP3A4
- Strong or moderate inducers of CYP3A4
- Patients participating in a migraine-related clinical trial.
Exclusion
Key Trial Info
Start Date :
November 15 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 31 2026
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT06898047
Start Date
November 15 2025
End Date
July 31 2026
Last Update
December 19 2025
Active Locations (1)
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1
Pfizer
London, United Kingdom