Status:
RECRUITING
The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis
Lead Sponsor:
First Affiliated Hospital of Wannan Medical College
Collaborating Sponsors:
Suzhou Municipal Hospital of Anhui Province
the Second of Affiliated Hospital of Wannan Medical College, Wuhu, China
Conditions:
Septic Cardiomyopathy
Septic Shock
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study focuses on improving heart function in patients with life-threatening blood infections (septic shock). When the body fights severe infections, the heart sometimes struggles to pump blood ef...
Eligibility Criteria
Inclusion
- 1\. Patients clinically diagnosed with septic shock must meet the diagnostic criteria of Sepsis 3.0;
- 2\. Age ≥ 18 years.
Exclusion
- 1\. Pregnant or breastfeeding women;
- 2\. Individuals with a history of allergies or known hypersensitivity to Ginseng and Aconite Injection or its components;
- 3\. Severe underlying diseases that may affect prognosis, including uncontrolled malignant tumors with multiple metastases that are unresectable, hematological disorders, cachexia, persistent active bleeding, severe malnutrition, HIV, etc.;
- 4\. Severe cardiac conditions within the last three months, including acute unstable myocardial infarction, dilated cardiomyopathy, acute coronary syndrome, acute or chronic valvular heart disease, and congestive heart failure (New York Heart Association \[NYHA\] Class IV);
- 5\. Any of the following medical procedures performed within the last three months: any form of cardiac surgery, thoracotomy, external cardiac compression, defibrillation, direct current cardioversion, or trauma;
- 6\. Use of Ginseng and Aconite Injection for less than 48 hours;
- 7\. Patients expected to die within 48 hours;
- 8\. Patients deemed unsuitable for this study by the investigator.
Key Trial Info
Start Date :
October 1 2024
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2026
Estimated Enrollment :
440 Patients enrolled
Trial Details
Trial ID
NCT06898723
Start Date
October 1 2024
End Date
September 30 2026
Last Update
March 27 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)
Wuhu, Anhui, China, 241001