Status:
NOT_YET_RECRUITING
Language Intervention Training for Cognitive Protection in High-risk Cardio-Cerebrovascular Elderly Population
Lead Sponsor:
Second Affiliated Hospital, School of Medicine, Zhejiang University
Conditions:
Vascular Cognitive Impairment No Dementia
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
The global population is aging rapidly, with the number of elderly people with dementia projected to rise sharply, posing significant challenges to quality of life and societal burden.Frequent languag...
Detailed Description
The global population is aging rapidly, with those aged 65+ expected to reach 16% of the total population by 2050. Aging is linked to increased cognitive impairment risks, including dementia prevalenc...
Eligibility Criteria
Inclusion
- Patients aged ≥ 60 years
- High risk of stroke (with ≥ 3 of 8 stroke risk factors, including hypertension, dyslipidemia, diabetes, atrial fibrillation or valvular heart disease, smoking history, obvious overweight or obesity, lack of exercise, family history of stroke, or with transient ischemic attack)
- command of Hangzhou dialect
- Written informed consent available
- Willingness to complete all assessments and participate in follow-up
- Adequate Visual and auditory acuity to undergo neuropsychological testing
Exclusion
- previously diagnosed dementia
- Suspected dementia after clinical assessment by study physician at screening visit
- Previous history of major head trauma and any intracranial surgery
- Intracranial abnormalities, such as intracerebral hemorrhage, subarachnoid hemorrhage and other space occupying lesions
- Extrapyramidal symptoms or mental illness which may affect neuropsychological measurement
- Severe loss of vision, hearing, or communicative ability
- Patients presenting a malignant disease with life expectancy \< 3 years
- Participation in an ongoing investigational drug study
- Any MRI contraindications
Key Trial Info
Start Date :
April 15 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 20 2026
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT06898931
Start Date
April 15 2025
End Date
September 20 2026
Last Update
March 27 2025
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