Status:

NOT_YET_RECRUITING

Clinicopathological Features , Outcomes and Prognostic Factors of High Risk Patients of Gestational Trophoblastic Neoplasia

Lead Sponsor:

Assiut University

Conditions:

Gestational Trophoblastic Neoplasias (GTN)

Eligibility:

FEMALE

Brief Summary

Aim of the Study This study aims to investigate the clinical and pathological features, treatment outcomes, and prognostic factors in high-risk patients with Gestational Trophoblastic Neoplasia (GTN)....

Detailed Description

Gestational trophoblastic disease (GTD) and gestational trophoblastic neoplasm (GTN) encompass a heterogeneous family of rare diseases that originate from fetal trophoblast cells during or after pregn...

Eligibility Criteria

Inclusion

  • • Patients diagnosed as high risk patient according to WHO classification\[10\]
  • Adequate clinical data available, including demographic, pathological, and treatment-related details.
  • Patients treated at Assuit university women's health hospital within a specified period (e.g., observational study covering period from Jan 2020 till dec 2025).

Exclusion

  • • Previous Malignancy - Patients with a history of other malignancies that may confound outcomes.
  • Non-GTN Gestational Trophoblastic Disease (GTD) - Patients with benign conditions such as complete or partial hydatidiform mole without progression to GTN.
  • Pregnant at Diagnosis - Patients diagnosed with GTN during an ongoing pregnancy.
  • Severe Comorbidities - Patients with significant non-GTN-related illnesses that could affect survival outcomes (e.g., severe heart, liver, or renal disease)

Key Trial Info

Start Date :

April 1 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

April 1 2027

Estimated Enrollment :

42 Patients enrolled

Trial Details

Trial ID

NCT06900699

Start Date

April 1 2025

End Date

April 1 2027

Last Update

March 28 2025

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Clinicopathological Features , Outcomes and Prognostic Factors of High Risk Patients of Gestational Trophoblastic Neoplasia | DecenTrialz