Status:
ACTIVE_NOT_RECRUITING
Effect of L-carnitine Supplementation on Phenylalanine and Brain-derived Neurotrophic Factor Levels in Infants and Children With Phenylketonuria
Lead Sponsor:
Mansoura University
Conditions:
Phenylketonuria
Eligibility:
All Genders
1-18 years
Phase:
PHASE4
Brief Summary
Effect of L-carnitine supplementation on phenylalanine and brain-derived neurotrophic factor levels in infants and children with phenylketonuria L-carnitine is mainly obtained from foods such as red ...
Detailed Description
Subjects And Methods : * Type of the study: Two phases: 1- Cross sectional comparative study ( PKU versus non PKU infants and children). 2- Open label Randomized controlled clinical trial for P...
Eligibility Criteria
Inclusion
- Male and female PKU patients diagnosed and following up at Genetics and Metabolic Outpatient Clinic.
- Age from one month up to 18 years
Exclusion
- Any patient with other metabolic, genetic or neurological diseases.
- Patients who and/or their guardians refused to sign the consent
Key Trial Info
Start Date :
February 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2026
Estimated Enrollment :
176 Patients enrolled
Trial Details
Trial ID
NCT06901323
Start Date
February 1 2025
End Date
August 1 2026
Last Update
April 4 2025
Active Locations (1)
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1
Mansoura University
Al Mansurah, Egypt