Status:
NOT_YET_RECRUITING
Role of Cytomorphometry and BRAFV600E Immunocytochemistry With a Cytologic Diagnosis "Suspicious for Papillary Thyroid Carcinoma"
Lead Sponsor:
Assiut University
Conditions:
Suspicious for Papillary Thyroid Carcinoma
Eligibility:
All Genders
Brief Summary
Thyroid nodules (TNs) are a common finding, detected by ultrasound in about 70% of healthy individuals, with women being four times more affected. While most TNs are benign, the primary clinical goal ...
Detailed Description
Thyroid nodules are common clinical finding in routine daily medical and surgical practice. They are discovered by ultrasonography in about 70% of clinically healthy individuals. Thyroid nodules are f...
Eligibility Criteria
Inclusion
- Only Papanicolaou (PAP) and Hematoxylin \& Eosin (H\&E) stained FNAC smears diagnosed as suspicious for papillary thyroid carcinoma will be included in the study.
- Only FNAC smears with well-preserved nuclear morphology will be included in the study.
- Smears with histopathological slides.
Exclusion
- FNAC smears lacking histopathological confirmation.
- Smears with extensive nuclear overlap and poor morphology.
- Smears obscured by inflammation, blood, or mucoid material.
- Smears exhibiting cellular degenerative changes or drying artifacts.
- Any patient with missing data.
Key Trial Info
Start Date :
May 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2027
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT06901908
Start Date
May 1 2025
End Date
November 1 2027
Last Update
April 3 2025
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