Status:
NOT_YET_RECRUITING
Dairy Choline Bioavailability
Lead Sponsor:
University of Wisconsin, Madison
Conditions:
Post-menopausal Women
Post-menopausal Status
Eligibility:
FEMALE
51-70 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to find out if dairy is a good source of choline compared to eggs. The main questions it aims to answer are: * How the body uses choline; and, * What effect WPPC ha...
Detailed Description
This study is intended to evaluate the bioavailability and metabolism of choline in WPPC compared to the most commonly -used food for bioavailable choline, whole egg. The intent of the evaluation is t...
Eligibility Criteria
Inclusion
- Ages between 51 and 70
- Is currently post-menopausal (Post-menopausal is a term used to describe the time in a woman's life after she has gone through menopause. This usually happens between the ages of 45 and 55. Menopause is when a woman's menstrual periods stop permanently (at least 12 months))
- Not allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds.)
- Had stable body weight (± 5%) for the past 6 months
- Free from cancer
- Did not have weight loss surgery, colon surgery
- Do not have chronic kidney diseases
- Do not have malabsorption towards fat and dairy products
- Willing to complete health surveys
- Willing to complete two 4-day food diaries
- Willing to consume the intervention beverages
- Willing to provide blood, urine, fecal samples at baseline and after 10 days of intervention
Exclusion
- On weight loss/weight gain diets
- Diagnosed with fat malabsorption
- Undergoing weight loss surgery
- Diagnosed with chronic kidney diseases
- Allergic to the intervention foods and allergens that are related to the production of intervention foods (e.g. dairy products, egg, chocolate, fish, peanut, shellfish, soy, tree nuts, wheat, crustaceans, gluten, mollusks, mustard, sesame seeds, banana, strawberry, raspberry, blackberry, blueberry.)
- Regularly using antibiotics or probiotics or prebiotics
- Regularly using Orlistat or Cetilistat
- Regularly using laxatives
- Undergoing hormone replacement therapy, or receiving hormones in any forms
- Unable to avoid strenuous exercise during the study (\>4 h intense exercise per day)
Key Trial Info
Start Date :
January 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
October 1 2026
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT06902480
Start Date
January 1 2026
End Date
October 1 2026
Last Update
November 26 2025
Active Locations (1)
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1
University of Wisconsin - Madison
Madison, Wisconsin, United States, 53705