Status:

COMPLETED

Impact of Prior SGLT2 Inhibitors Use on the Development and Progression of Sepsis-Associated Acute Kidney Injury

Lead Sponsor:

University of Jazan

Conditions:

Sepsis

Septic Shock

Eligibility:

All Genders

18-75 years

Brief Summary

The primary objective of this study is to investigate whether using SGLT2i may be associated with decreased incidence of sepsis-induced AKI or not.

Detailed Description

The primary objective of this study is to investigate whether using SGLT2i may be associated with decreased incidence of sepsis-induced AKI or not.

Eligibility Criteria

Inclusion

  • All adult (≥ 18 year) patients who were admitted to ICU with sepsis syndromes (sepsis or septic shock), according to sepsis-3 definition.

Exclusion

  • Missing data
  • Renal transplant or tumor
  • Solitary kidney
  • Established CKD
  • Obstructive uropathy
  • Renal artery stenosis
  • Pregnancy

Key Trial Info

Start Date :

April 1 2024

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 1 2025

Estimated Enrollment :

664 Patients enrolled

Trial Details

Trial ID

NCT06902493

Start Date

April 1 2024

End Date

March 1 2025

Last Update

March 30 2025

Active Locations (1)

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1

King Fahd Central Hospital

Al ‘Usaylah, Saudi Arabia