Status:

ACTIVE_NOT_RECRUITING

Post-authorization Safety Study of Iptacopan in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Using Data From the IPIG PNH Registry

Lead Sponsor:

Novartis Pharmaceuticals

Conditions:

Hemoglobinuria, Paroxysmal

Eligibility:

All Genders

18-100 years

Brief Summary

This is an observational single-arm descriptive cohort study based on the secondary use of data collected on iptacopan-treated patients with paroxysmal nocturnal hemoglobinuria (PNH) through the Inter...

Detailed Description

This multinational, non-interventional, descriptive single-arm cohort study is based on secondary analysis of data collected within the iptacopan silo of the IPIG PNH Registry (data on iptacopan-treat...

Eligibility Criteria

Inclusion

  • Signed informed consent to participate in the IPIG PNH Registry
  • PNH confirmed by flow cytometry
  • Incident users of iptacopan
  • Aged at least 18 years at the iptacopan initiation

Exclusion

  • Participation in an interventional clinical trial

Key Trial Info

Start Date :

March 31 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2029

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT06903234

Start Date

March 31 2025

End Date

October 1 2029

Last Update

May 15 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Novartis Investigative Site

Basel, Switzerland