Status:

NOT_YET_RECRUITING

Pentoxifylline for Vascular Calcification in Kidney Disease

Lead Sponsor:

Mansoura University

Conditions:

Chronic Kidney Disease

Vascular Calcification

Eligibility:

All Genders

18+ years

Phase:

PHASE1

PHASE2

Brief Summary

This study is research to find out if the drug pentoxifylline can help prevent or lessen the problem of blood vessel hardening (vascular calcification) in people with chronic kidney disease (CKD). Peo...

Eligibility Criteria

Inclusion

  • Estimated Glomerular Filtration Rate (eGFR) less than 60 ml/min/1.73 m² and greater than or equal to 15 ml/min/1.73 m².
  • Adult patients, age 18 years or older.
  • Diagnosis of Chronic Kidney Disease (CKD).
  • Willing and able to provide informed consent.

Exclusion

  • Patients currently undergoing regular hemodialysis.
  • History of kidney transplantation or are kidney transplant recipients.
  • Pregnant females.
  • Patients with a history of coronary artery bypass grafting (CABG).
  • Known allergy or contraindication to pentoxifylline.
  • Inability to comply with study procedures or attend follow-up visits.

Key Trial Info

Start Date :

April 15 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 30 2025

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT06903689

Start Date

April 15 2025

End Date

October 30 2025

Last Update

April 1 2025

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