Status:

NOT_YET_RECRUITING

The Effects of Eccentric Compared to Standard Strength Training in Primary Spinal Cord Injury Rehabilitation

Lead Sponsor:

Swiss Paraplegic Research, Nottwil

Conditions:

Spinal Cord Injury

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The goal of this clinical trial is to assess the effects of eccentric arm-crank (KREHA) training compared to standard clinical routine strength (STAN) training in individuals undergoing primary spinal...

Eligibility Criteria

Inclusion

  • 18 years or older.
  • informed consent as confirmed per signature.
  • traumatic or disease-related SCI.
  • participating in the routine strength training program during primary SCI rehabilitation at the study center (generally this is initiated around one month after SCI onset).
  • wheelchair dependency during activities of daily living, defined by a score of 0-2 in the SCIM subsection regarding "Mobility in the house".
  • passed sports medical assessment and having sufficient biceps/triceps function to perform arm-crank training, as determined by an experienced sports medicine physician

Exclusion

  • inflammatory or neurodegenerative diseases (including multiple sclerosis or Guillain-Barré syndrome).
  • comorbidities or other health issues that may interfere with study participation, inability or contraindications to undergo the investigated intervention.
  • MRI contraindications (magnetic metal parts or electronic implants such as pacemakers in the body).
  • pregnancy (anamnestic).

Key Trial Info

Start Date :

March 1 2026

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2028

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06905470

Start Date

March 1 2026

End Date

March 1 2028

Last Update

December 2 2025

Active Locations (1)

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1

Swiss Paraplegic Centre

Nottwil, Canton of Lucerne, Switzerland, 6207