Status:

RECRUITING

Validating a Clinical Prediction Rule to Guide Manual Therapy and Exercise for Neck Pain Relief in 140 Participants With Neck Pain

Lead Sponsor:

Baylor University

Collaborating Sponsors:

Foundation for Physical Therapy Research

Conditions:

Neck Pain Musculoskeletal

Neck Pain Treatment

Eligibility:

All Genders

18-70 years

Phase:

NA

Brief Summary

Neck pain is a common issue that can lead to long-term disability and lost work time for many individuals. Despite numerous studies, finding effective treatment strategies has been challenging. One po...

Detailed Description

This study's primary objective will examine whether a previously derived clinical prediction rule (CPR) exhibits validity for identifying a subgroup of patients who respond favorably to cervical thrus...

Eligibility Criteria

Inclusion

  • Ages 18 to 70
  • Primary complaint of neck pain with or without unilateral upper extremity symptoms
  • Neck Disability Index (NDI) score of 10 or greater
  • Numeric Pain Rating Scale score of 2 or greater

Exclusion

  • History of whiplash injury within the past 6 weeks
  • Diagnosis of cervical spinal stenosis
  • Bilateral upper extremity symptoms
  • Red flags noted in the patient's Neck Medical Screening Questionnaire (i.e. tumor, fracture, rheumatoid arthritis, osteoporosis, severe atherosclerosis, dizziness, diplopia, drop attacks, bilateral numbness, nausea, prolonged history of steroid use)
  • Evidence of central nervous system involvement, to include hyperreflexia, sensory disturbances in the hand, intrinsic muscle wasting of the hands, unsteadiness during walking, nystagmus, loss of visual acuity, impaired sensation of the face, altered taste, the presence of pathological reflexes (i.e. positive Hoffman's and/or Babinski reflexes)
  • Two or more positive neurological signs consistent with significant nerve root compression, including any two of the following:
  • Muscle weakness involving a major muscle group of the upper extremity
  • Diminished upper extremity muscle stretch reflex (biceps, triceps, or brachioradialis)
  • Diminished or absent sensation to pinprick or light touch in any upper extremity dermatome
  • Prior neck surgery
  • Current pregnancy, pregnancy within 6 months, or currently lactating
  • Pending legal action pertaining to their neck pain
  • Inability to read English at the 8th grade reading level
  • Inability to legally provide informed consent for any other reason
  • Inability to comply with the treatment and follow-up schedule

Key Trial Info

Start Date :

June 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT06906107

Start Date

June 1 2025

End Date

December 31 2026

Last Update

June 18 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

ActivePT

Rochester, Minnesota, United States, 55901

2

PROActivePT

Syracuse, New York, United States, 13201

3

ActiveTherapy Alliance

Waco, Texas, United States, 76798