Status:
ENROLLING_BY_INVITATION
Transcriptional Changes in Isolated Human Adipocytes During Obesity
Lead Sponsor:
University of Southern Denmark
Collaborating Sponsors:
Bispebjerg Hospital
Conditions:
Obesity, Abdominal
Adiposity
Eligibility:
All Genders
18+ years
Brief Summary
Adipocytes play an important role in our body through their function as metabolic energy stores in the form of fat deposits, which are stored when metabolic energy is in excess and released when energ...
Detailed Description
The development of overweight and obesity is associated with major changes in adipose tissue, including structural changes in cell type composition as well as gene expression in individual adipose tis...
Eligibility Criteria
Inclusion
- Age \> 18 years old
- BMI\> 19 kg/m2
- Can receive oral and written information and give appropriate consent
Exclusion
- Active viral hepatitis, HIV positive
- Autoimmune diseases (i.e. lupus)
- Chronic use of corticosteroids (cortisone)
- Unable to give appropriate consent
- Contraindications for biopsy: bleeding tendency.
- Cancer or other comorbidity with an expected survival time of less than 12 months
Key Trial Info
Start Date :
April 1 2023
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 1 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06907212
Start Date
April 1 2023
End Date
September 1 2025
Last Update
April 2 2025
Active Locations (1)
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1
Bispebjerg hospital
Copenhagen, Denmark, 2400