Status:
NOT_YET_RECRUITING
Comparison of Sevoflurane and Propofol on ANI
Lead Sponsor:
Pusan National University Yangsan Hospital
Conditions:
Propofol
Sevoflurane
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
The goal of this clinical trial is to compare the effect of sevoflurane and propofol on analgesia nociception index(ANI) in patients undergoing general anesthesia. The main question it aims to answer ...
Detailed Description
Patients will be allocated to either propofol or sevoflurane group. Nociceptive event will be defined as long-lasting tetanic stimulation, square-wave, duration of 30 seconds , amplitude of 50mA, freq...
Eligibility Criteria
Inclusion
- American society of anesthesiologists physical status class I or II
Exclusion
- history of drugs that can affect the central nervous system and autonomic nervous system, such as anticholinergics, betablockers, antidepressants..etc.
- history of allergic reaction to sevoflurane and/or propofol
- history of and/or family history of malignant hyperthermia
- neurodegenerative disorder
- psychiatric disorder
- arrhythmia
- diabetes mellitus
- drug abuse history
Key Trial Info
Start Date :
June 30 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT06907823
Start Date
June 30 2025
End Date
December 31 2025
Last Update
June 10 2025
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