Status:

ACTIVE_NOT_RECRUITING

Assessing the Therapeutic Potential of a Traditional Botanical Remedy for Menstrual Pain: Insights From a Prospective Observational Analysis

Lead Sponsor:

University of Zurich

Conditions:

Dysmenorrhea Primary

Eligibility:

FEMALE

18-45 years

Phase:

PHASE4

Brief Summary

Primary dysmenorrhea (PDM) affects round 60 to 90% of women and has a great impact on everyday life of affected women, leading to decreased work productivity, cognitive activity and cuts in social lif...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Age between 18 and 45 years with regular menstrual cycles (21-35 days)
  • Menstrual pain rated 6 or higher on an 11-point PI-NRS during the most painful day
  • In good general health
  • Provided written informed consent
  • Willing to maintain the same personal hygienic product throughout the study (e.g., tampons, pads, menstrual cups; no changes in menstrual hygiene practices allowed during the study)
  • Exclusion Criteria
  • Secondary dysmenorrhea (i.e. in endometriosis, adenomyosis, urogenital malformations)
  • Currently taking, or had taken in the past two months, hormonal forms of birth control
  • Dysmenorrhea reasonably suspected to be due to a IUD
  • Prior or current liver or kidney disease, inflammatory bowel disease, reproductive cancer (uterine, ovarian, etc.)
  • Personal history of known hypersensitivity to the used drug or its ingredients or to drugs with a similar chemical structure
  • Other diseases that do not allow the subject to assess the nature and scope as well as possible consequences of the clinical study
  • Pregnant or breastfeeding women
  • Signs that the subject is unlikely to comply with the protocol (e.g., unwillingness to cooperate)
  • Alcohol/drug abuse
  • Non-German speaking patients (Patient information is only available in German)

Exclusion

    Key Trial Info

    Start Date :

    January 1 2025

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 31 2028

    Estimated Enrollment :

    25 Patients enrolled

    Trial Details

    Trial ID

    NCT06908044

    Start Date

    January 1 2025

    End Date

    December 31 2028

    Last Update

    April 10 2025

    Active Locations (2)

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    Page 1 of 1 (2 locations)

    1

    Private Centre for Obstetrics and Gynecology "Geburt und Familie"

    Aarau, Canton of Aargau, Switzerland, 5000

    2

    Paracelsus Zentrum am Grossmünster

    Zurich, Canton of Zurich, Switzerland, 8001

    Assessing the Therapeutic Potential of a Traditional Botanical Remedy for Menstrual Pain: Insights From a Prospective Observational Analysis | DecenTrialz