Status:

RECRUITING

Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome

Lead Sponsor:

University Hospital, Bordeaux

Conditions:

Tourette Syndrome

Eligibility:

All Genders

16+ years

Phase:

NA

Brief Summary

Tourette syndrome (TS) is a complex neurodevelopmental disorder characterized by the occurrence of involuntary movements (motor tics) and vocalizations (phonic tics). The onset of TS is usually in chi...

Eligibility Criteria

Inclusion

  • Patient at least 16 years old.
  • Disabling and drug-resistant Tourette's syndrome.
  • Receiving deep brain stimulation treatment with implantation of the PERCEPT™ Device as part of their medical management.
  • Normal brain MRI.
  • Subject affiliated or beneficiary of a social security system.
  • Free and informed consent of the patient and, for minors, of the minor and at least one parental authority.

Exclusion

  • Major depressive syndrome (Beck Depression Inventory (BDI-II) \> 20).
  • MRI showing significant brain atrophy or significant hyperintensities.
  • Pregnant or nursing mothers.
  • Person unable to give personal consent.
  • Person subject to a legal protection measure (curatorship, guardianship) or placed under court protection.
  • Patient included in another research protocol with an interdiction of participation to another research or in an exclusion period

Key Trial Info

Start Date :

February 17 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 17 2027

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT06909656

Start Date

February 17 2025

End Date

February 17 2027

Last Update

April 3 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

CHU de Bordeaux

Bordeaux, France, 33076

Multimodal Electrophysiological Study of Cortico-subcortical Biomarkers of Tics in Tourette Syndrome | DecenTrialz