Status:
RECRUITING
Hemodynamic Evaluation Using Microcirculation for Early Treatment of Septic Patients
Lead Sponsor:
University Hospital, Limoges
Conditions:
Sepsis
Emergency Care
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Despite early treatment, the deterioration and mortality of sepsis patients remains high. A possible explanation could be persistent tissue hypoperfusion, or undetected in the early phase despite the ...
Detailed Description
Sepsis and its most serious form, septic shock, are a public health problem. Sepsis is defined by the presence of organ failure, including acute circulatory failure, which combines hypovolemia, vasopl...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Admitted to the Emergency Department for suspected Sepsis for less than 6 hours according to international Sepsis-3 definitions (high probability of infection defined by a fever greater than or equal tol to 38.3°C with a suspected infectious source + Score NEWS 2 greater than or equal to 2)
- Affiliated to a social security system
- Having agreed to participate in this study
Exclusion
- Patient with arterial hypotension (SBP ≤ 100 mmHg) on admission
- Patient having already received a 500mL filling test over 30 minutes
- Patients moribund according to the investigator
- Pregnancy or breastfeeding
- Patient under guardianship, curatorship or safeguard of justice
Key Trial Info
Start Date :
September 20 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 28 2027
Estimated Enrollment :
556 Patients enrolled
Trial Details
Trial ID
NCT06910891
Start Date
September 20 2025
End Date
March 28 2027
Last Update
November 21 2025
Active Locations (6)
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1
Brive Hospital
Brivé, France, 19100
2
Guéret Hospital
Guéret, France, 23000
3
Limoges University Hospital
Limoges, France, 87000
4
Saint Junien Hospital
Saint-Junien, France, 87200