Status:
RECRUITING
Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease
Lead Sponsor:
Massachusetts General Hospital
Collaborating Sponsors:
University of Miami Sylvester Comprehensive Cancer Center
Conditions:
Bone Marrow Transplant Complications
Graft-versus-Host Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and ...
Detailed Description
This is a randomized clinical trial to determine whether a multidisciplinary group-based telehealth intervention is effective at improving the quality of life and reducing psychosocial distress in pat...
Eligibility Criteria
Inclusion
- Adult patients (≥ 18 years) who have undergone allogeneic HCT
- Have moderate to severe cGVHD based on patient-report
- Have ability to participate in English or Spanish language group telehealth intervention.
Exclusion
- Patients with mild cGVHD based on their self-report.
- Patients with a major untreated psychiatric or cognitive condition which the treating oncology clinicians believes interferes with the capacity to provide informed consent.
Key Trial Info
Start Date :
August 13 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2030
Estimated Enrollment :
350 Patients enrolled
Trial Details
Trial ID
NCT06910969
Start Date
August 13 2025
End Date
February 1 2030
Last Update
October 15 2025
Active Locations (2)
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1
University of Miami Sylvester Comprehensive Cancer Center
Miami, Florida, United States, 33136
2
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114