Status:
RECRUITING
Bilateral Single-Electrode VO Combined With STN-DBS for Treating Meige Syndrome
Lead Sponsor:
Huashan Hospital
Conditions:
Meige Syndrome
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Meige syndrome is a rare and debilitating movement disorder characterized by blepharospasm, oromandibular dystonia, and cervical muscle contractions, often refractory to pharmacological therapies. Dee...
Detailed Description
While deep brain stimulation (DBS) targeting the subthalamic nucleus (STN) or the globus pallidus interna (GPi) has shown moderate efficacy, incomplete symptom relief and high stimulation thresholds w...
Eligibility Criteria
Inclusion
- Must meet the clinical diagnostic criteria for Meige syndrome
- Only includes patients with: Blepharospasm-type Meige syndrome and Blepharospasm with lower jaw muscle dystonia-type
- All patients must have undergone at least one year of systematic and standard treatment prior to surgery
Exclusion
- History of neurological diseases other than Meige syndrome
- Severe cognitive impairment
- Severe psychiatric disorders
Key Trial Info
Start Date :
March 6 2025
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2027
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06912282
Start Date
March 6 2025
End Date
January 1 2027
Last Update
April 4 2025
Active Locations (1)
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1
Huashan Hospital, Fudan University.
Shanghai, Shanghai Municipality, China, 200040