Status:
RECRUITING
Neural Mechanisms and Clinical Applications of DBS for Modulating Sleep Dysregulation in PD
Lead Sponsor:
Xuanwu Hospital, Beijing
Conditions:
Deep Brain Stimulation
Parkinson's Disease and Parkinsonism
Eligibility:
All Genders
19-80 years
Brief Summary
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by both motor and non-motor symptoms. Subthalamic nucleus (STN) deep brain stimulation (DBS) effectively alleviates mot...
Detailed Description
This single-center longitudinal observational study will enroll 20 idiopathic Parkinson's disease (PD) patients with bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) systems (Medtronic...
Eligibility Criteria
Inclusion
- Diagnosis of Parkinson's disease: The diagnostic criteria for Parkinson's disease are the Clinical Diagnostic Criteria of UK PD Society Brain Bank Clinical Diagnostic Criteria or 2015 MDS Clinical Diagnostic Criteria for PD.All diagnoses of Parkinson's disease were made by three neurologists who were experienced in the field of movement disorders.
- Patients who underwent bilateral STN-DBS(Medtronic Percept™ PC)
- Patients who can cooperate with the completion of postoperative follow-up and clinical evaluation.
Exclusion
- Patients who underwent other brain surgery;
- Other patients with secondary Parkinson's syndrome and Parkinsonism-plus syndrome;
- Patients with other central nervous system and peripheral nervous system diseases;
- Patients complicated with severe medical system diseases, or unable to tolerate clinical evaluation;
- Patients with severe mental illness;
- Patients who cannot complete informed consent due to cognitive and communication barriers, or refuse to sign informed consent.
Key Trial Info
Start Date :
September 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2026
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT06914466
Start Date
September 1 2024
End Date
December 1 2026
Last Update
April 6 2025
Active Locations (1)
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1
Xuanwu Hospital,Capital Medical University
Beijing, Beijing Municipality, China, 100053