Status:
NOT_YET_RECRUITING
Study on PAD and CAS Based on Omics and Imaging
Lead Sponsor:
Yijie Ning
Conditions:
Peripheral Artery Disease
Carotid Artery Stenosis
Eligibility:
All Genders
18-85 years
Brief Summary
This study aims to investigate the pathogenesis of Peripheral Artery Disease (PAD) and Carotid Artery Stenosis (CAS) using a comprehensive multi-omics and multi-modal imaging approach. The study will ...
Detailed Description
Background and Rationale Peripheral Artery Disease (PAD) and Carotid Artery Stenosis (CAS) are prevalent vascular disorders associated with significant morbidity and mortality. Despite advances in dia...
Eligibility Criteria
Inclusion
- The study subjects are inpatients from the Department of Vascular Surgery at the Second Hospital of Shanxi Medical University.
- Males or females aged between 18 and 85 years.
- Diagnosed with Peripheral Artery Disease (PAD) or Carotid Artery Stenosis (CAS).
- Participants are conscious, fully informed about the study content, and have signed the informed consent form, agreeing to participate in this study.
Exclusion
- Non-atherosclerotic stenosis (e.g., vasculitis or dissection).
- PAD patients who have previously undergone interventional treatments (e.g., balloon angioplasty or stent placement) and/or surgical procedures.
- Patients with heart failure classified as NYHA Class II-IV or those with a history of coronary artery disease.
- Patients with acute infections, tumors, severe arrhythmias, psychiatric disorders, or drug/alcohol addiction.
- Significant liver dysfunction or a history of liver diseases, including: Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) levels exceeding twice the upper limit of normal. History of cirrhosis, hepatic encephalopathy, esophageal varices, or portosystemic shunt.
- Significant renal dysfunction or a history of kidney diseases, including: Serum creatinine levels exceeding 1.5 times the upper limit of normal. History of dialysis or nephrotic syndrome.
- Pregnant women, those planning to become pregnant, or breastfeeding women.
- Participation in other clinical trials within the past 3 months.
- Refusal to sign the informed consent form or participate in this study.
Key Trial Info
Start Date :
April 1 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT06917547
Start Date
April 1 2025
End Date
October 1 2025
Last Update
April 8 2025
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.