Status:

RECRUITING

Management of Moderate to Severe Monotraumatic Pain With Sublingual Sufentanil in an Emergency Situation.

Lead Sponsor:

University Hospital, Clermont-Ferrand

Conditions:

Pain Management

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

Pain is a common reason for emergency department (ED) visits. However, studies suggest that emergency physicians may not always provide optimal analgesic treatment due to various factors, such as time...

Eligibility Criteria

Inclusion

  • Adult patient
  • Patient with a pain rating on the Numerical Rating Scale (NRS) ≥ 4
  • Pain of monotraumatic origin in the upper or lower limb
  • Glasgow Coma Scale = 15
  • SaO2 \> 95% in ambient air

Exclusion

  • Polytrauma
  • Analgesic treatment within the 4 hours preceding admission (except paracetamol)
  • Woman of childbearing age without effective contraception, declaring pregnancy or at risk of pregnancy, breastfeeding woman, or positive pregnancy test at inclusion
  • Patient requiring intravenous access upon admission (e.g., displaced open fracture)
  • Contraindication or allergy to any of the molecules in the analgesia protocol
  • Refusal to participate
  • Known substance abuse or psychiatric disorders
  • Known oxygen dependence or COPD
  • Not affiliated with social security
  • Patient under guardianship, curatorship, deprived of liberty, or under legal protection
  • Patient who does not speak or read French

Key Trial Info

Start Date :

April 22 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 31 2026

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT06917651

Start Date

April 22 2025

End Date

January 31 2026

Last Update

April 29 2025

Active Locations (1)

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1

CHU de Clermont-Ferrand, Clermont-Ferrand

France, France