Status:

COMPLETED

Effect of CGF on Postoperative Pain After Third Molar Surgery

Lead Sponsor:

Ege University

Conditions:

Oral Complication

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on pain after bilateral impacted third molar surgery and to determine its contribution to the healing process. ...

Eligibility Criteria

Inclusion

  • Patients with bilateral, symmetrical, bone-retained (vertical, mesioangular, horizontal) impacted wisdom teeth in the mandible, regardless of gender
  • Patients without any systemic disease
  • Patients who have been informed about the duration, purpose and requirements of the study and who have signed the informed consent form voluntarily.

Exclusion

  • Having a disease affecting general health that requires the application of prophylactic antimicrobial agents
  • Having a systemic viral, fungal or bacterial infection
  • Patients with acute or chronic maxillary sinusitis
  • Suspected or diagnosed pregnancy and nursing mothers
  • Patients with heart and vascular diseases
  • Patients with liver disease, haematological disease and neoplastic disease
  • Patients who have recently received anti-inflammatory therapy
  • Patients with chronic medication use (antihistamines, NSAIDs, steroids and antidepressants)
  • Patients predisposed to psychotic or psychopathic tendencies
  • Patients with rheumatic diseases, blood diseases, diabetes mellitus
  • Patients at cardiological risk of infective endocarditis
  • Patients under antibiotic pressure

Key Trial Info

Start Date :

May 1 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 5 2018

Estimated Enrollment :

49 Patients enrolled

Trial Details

Trial ID

NCT06918327

Start Date

May 1 2017

End Date

June 5 2018

Last Update

April 20 2025

Active Locations (1)

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Ege University Faculty of Dentistry

Izmir, Bornova, Turkey (Türkiye), 35040