Status:
COMPLETED
Ultrasonographic Evaluation of the Effects of Different Wrist Positions on the Median Nerve in Patients With Generalized Joint Hypermobility
Lead Sponsor:
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Conditions:
Hypermobility Syndrome (Disorder)
Ultrasonography
Eligibility:
FEMALE
15-45 years
Brief Summary
The aim of this study was to evaluate the effects of different wrist positions (neutral, flexion, extension, and ulnar deviation) on median nerve morphology in patients with generalized joint hypermob...
Detailed Description
This prospective cross-sectional study will include 18 female patients diagnosed with GJH (Beighton score ≥5) and 18 healthy volunteers with similar age, gender, and body mass index. Both wrists of al...
Eligibility Criteria
Inclusion
- 15-45 years of age
- Female gender
- Diagnosed with GJH according to the hypermobility spectrum disorders definition
- Patients who agree to participate in the study and provide written consent
Exclusion
- Having wrist pain
- Inability to complete full range of motion in the wrist joint
- Patients diagnosed with carpal tunnel syndrome
- Anatomical abnormalities (bifid median nerve, aberrant persistent median artery, Martin-Gruber or other anastomoses)
- History of trauma, operation, fracture, or steroid injection of the hand/wrist
- History of known rheumatological, hereditary, genetic disease, or connective tissue disease other than GJH
- Having neurological disease affecting hand functions (cervical radiculopathy, peripheral nerve lesion, polyneuropathy, cerebrovascular event, etc.)
- Patients with history of regular steroid or non-steroid use, receiving oral glucosamine/hyaluronate supplementation
- Those with systemic diseases (inflammatory joint diseases, diabetes mellitus, acromegaly, hypothyroidism, kidney failure, etc.)
- Having a body mass index (BMI) of 30 or above, or history of morbid obesity
- Being pregnant or in lactation period
- Presence of malignancy
Key Trial Info
Start Date :
February 1 2024
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 28 2025
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT06918613
Start Date
February 1 2024
End Date
June 28 2025
Last Update
November 20 2025
Active Locations (1)
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1
Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Istanbul, Bahçelievler, Turkey (Türkiye), 34158