Status:

RECRUITING

STI Testing to Enhance PrEP Use in Pregnancy

Lead Sponsor:

Botswana Harvard AIDS Institute Partnership

Collaborating Sponsors:

University of Washington

University of Botswana

Conditions:

PrEP Adherence

Sexually Transmitted Infections (STIs)

Eligibility:

FEMALE

Phase:

PHASE3

Brief Summary

The investigators are conducting a study in Botswana to see if offering STI testing along with expanded HIV prevention options (PrEP) helps more pregnant women start and continue using PrEP during and...

Detailed Description

The investigators are conducting a 2-arm 1:1 randomized trial to compare PrEP delivery with co-offer of STI testing for Chlamydia trachomatis, Neisseria gonorrhoeae and Trichomonas vaginalis (using Xp...

Eligibility Criteria

Inclusion

  • Pregnant and seeking antenatal care
  • Self-identifying as a cis-gender woman
  • Living without HIV
  • Not currently using PrEP
  • Planning to remain in the city/town of enrolment until 9 months post-delivery.
  • Planning to receive antenatal and postnatal care in the city/town of enrolment.
  • Willing and able to provide informed consent

Exclusion

  • Male gender
  • Not pregnant
  • Living with HIV
  • Currently using PrEP
  • Not planning to remain in the city/town of enrolment until 9 months post-delivery
  • Not planning to receive antenatal and postnatal care in the city/town to enrolment
  • Not able or willing to provide informed consent for participation

Key Trial Info

Start Date :

June 18 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 31 2029

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT06919614

Start Date

June 18 2025

End Date

August 31 2029

Last Update

July 29 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

DHMT Clinics

Gaborone, Botswana

STI Testing to Enhance PrEP Use in Pregnancy | DecenTrialz