Status:
COMPLETED
Effect of Ephedrine vs. Norepinephrine on Prevention of Fetal Acidosis During Cesarean Section Under Spinal Anesthesia
Lead Sponsor:
mehmet özkılıç
Conditions:
Cesarean Delivery Affecting Newborn
Acidosis
Eligibility:
FEMALE
18-45 years
Phase:
PHASE4
Brief Summary
This study compares the effects of two medications, ephedrine and norepinephrine, on the baby (fetus) when used to treat low blood pressure (hypotension) during cesarean section under spinal anesthesi...
Detailed Description
This is a prospective, randomized, double-blind, controlled clinical trial designed to compare the effects of ephedrine and norepinephrine on fetal acidosis during cesarean section performed under spi...
Eligibility Criteria
Inclusion
- Pregnant women aged between 18 and 45 years
- Singleton pregnancy at ≥ 37 weeks of gestation
- Scheduled for elective cesarean section under spinal anesthesia
- ASA (American Society of Anesthesiologists) physical status classification I or II
- Ability to understand and sign the informed consent form
Exclusion
- History of allergy or hypersensitivity to ephedrine or norepinephrine
- Multiple gestation pregnancies
- Diagnosis of pre-eclampsia, eclampsia, or other hypertensive disorders of pregnancy
- Known cardiovascular disease or arrhythmia
- Placental abnormalities (e.g., placenta previa, placental abruption)
- Fetal structural or chromosomal anomalies
- Morbid obesity (BMI \> 40 kg/m²)
- Refusal to participate or inability to provide informed consent
Key Trial Info
Start Date :
September 1 2025
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 15 2025
Estimated Enrollment :
102 Patients enrolled
Trial Details
Trial ID
NCT06921473
Start Date
September 1 2025
End Date
December 15 2025
Last Update
December 29 2025
Active Locations (1)
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1
SBÜ Gazi Yaşargil Eğitim ve Araştırma Hastanesi
Diyarbakır, Turkey (Türkiye), 21070