Status:
COMPLETED
Simplified Inferior Vena Cava Collapsiblity
Lead Sponsor:
University Hospital, Lille
Conditions:
Circulatory Failure
Eligibility:
All Genders
18+ years
Brief Summary
Fluid administration is a cornerstone therapy in critically ill patient. Fluid restriction or overload can therefore change patient's outcome and mortality. Close monitoring of PR (capacity of increas...
Detailed Description
The primary objective of this study is to confirmed the excellent accuracy of cVCI to predict PR when standardized inspiratory maneuver is simplified. The secondary objective is to test cVCIs in diff...
Eligibility Criteria
Inclusion
- Patient requiring an evaluation of PR by echocardiography for
- Presence of at least one clinical sign of acute circulatory failure (Mean Arterial Pressure \< 65 mmHg, mottling, tachycardia with Heart Rate \> 90 bpm, capillary refill time \> 3 sec, oliguria (urine output \< 0,5 mL/kg/h over 1 hour or more))
- Noradrenaline administration
- Age \> 18 years old
- Spontaneous breathing patient requiring oxygen administration without mechanical assistance
Exclusion
- Intolerance of inspiratory maneuver defined by:
- Clinical sign of acute respiratory failure
- Active abdominal expiration
- Hemodynamic response of passive leg raising not evaluable:
- Intracranial hypertension
- Impaired transthoracic or abdominal echogenicity
- High grade aortic insufficiency
- Pregnancy
- Abdominal compartment syndrome
- Lower limb amputation
- Urgent hemodynamic therapy within half an hour
- Modification of hemodynamic support (fluid therapy or modification of catecholamine dose)
Key Trial Info
Start Date :
June 6 2023
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 7 2024
Estimated Enrollment :
74 Patients enrolled
Trial Details
Trial ID
NCT06921642
Start Date
June 6 2023
End Date
June 7 2024
Last Update
April 10 2025
Active Locations (1)
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1
Lille University Hospital
Lille, France