Status:

RECRUITING

Virtual Reality Exposure for Vaginismus: A Replicated Single-Case Design

Lead Sponsor:

University of British Columbia

Collaborating Sponsors:

Canadian Institutes of Health Research (CIHR)

Conditions:

Vaginismus

Eligibility:

FEMALE

19+ years

Phase:

NA

Brief Summary

Vaginismus is a sexual dysfunction characterized by involuntary tightening of the pelvic floor muscles, preventing vaginal intercourse. It is defined by an intense fear of vaginal penetration, leading...

Detailed Description

Purpose/Aims: VR is a new, powerful technology that, if effective, can directly improve clinical care offered to those suffering from vaginismus across Canada. This study will advance health-related ...

Eligibility Criteria

Inclusion

  • The investigators will recruit individuals who have a vagina. They expect that most participants will identify as cisgender, where sex is female and gender is woman, while others may have a female sex but identify as a different gender (e.g., genderdiverse). Transwomen (i.e., birth assigned males but identify as woman) who have had gender-affirming surgery (and so have a vagina) are eligible, as are transmen (i.e., birth assigned females but identify as men) who have not had bottom surgery (so have a vagina).
  • Inclusion criteria: In addition to having a vagina, participants must have a diagnosis of vaginismus that requires self-reported involuntary tightness of the vaginal musculature that causes persistent interference with vaginal penetration lasting \>6 months; aged \>19 y, of any sexual orientation. Participants must be fluent in English (psychoeducational materials and questionnaires delivered in English), have normal or corrected-to-normal vision (to view the VR scenes during exposure), and be able to travel to Vancouver.

Exclusion

  • Presence of: unprovoked vaginal pain; a vulvar skin condition (i.e., lichen sclerosus); an imperforate hymen; or epilepsy characterized by photosensitive seizures. Note: provoked vulvar pain is not an exclusion criterion because at least 40% of people with vaginismus report pain with attempted penetration.

Key Trial Info

Start Date :

April 1 2025

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

January 30 2027

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06923306

Start Date

April 1 2025

End Date

January 30 2027

Last Update

September 25 2025

Active Locations (2)

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Page 1 of 1 (2 locations)

1

UBC Sexual Health Lab, Vancouver Hospital

Vancouver, British Columbia, Canada, V5M 1M9

2

Diamond Health Care Centre

Vancouver, British Columbia, Canada, V5Z1M9