Status:
ACTIVE_NOT_RECRUITING
Application of Salivary Biomarkers in Risk Assessment for Oral Diseases in Children With Type 1 Diabetes
Lead Sponsor:
University of Novi Sad
Conditions:
Biomarkers
Saliva
Eligibility:
All Genders
6-18 years
Brief Summary
This research contributes to a deeper understanding of the etiopathogenesis of periodontal and other oral diseases in children with T1D. By analyzing the composition of the salivary microbiome and det...
Detailed Description
Diabetes mellitus (DM) is a metabolic disorder characterized by impaired metabolism of carbohydrates, fats, and proteins. As a chronic disease, it leads to numerous systemic complications (1). Type 1 ...
Eligibility Criteria
Inclusion
- Age of subjects from 6 to 18 years, both sexes, with mixed or permanent dentition present.
- An experimental group of at least 56 subjects will be children diagnosed with DM type 1 (at least one year)
- The control group includes at least 56 subjects, healthy children, who match the tested group in gender and age, with the absence of acute diseases.
Exclusion
- Uncooperative patient
- Associated diseases
- Unsigned informative consent from the data subject/parent/guardian
- Antibiotic use in the last few months
- Subjects with orthodontic appliances
Key Trial Info
Start Date :
January 31 2025
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
112 Patients enrolled
Trial Details
Trial ID
NCT06924372
Start Date
January 31 2025
End Date
December 1 2025
Last Update
April 11 2025
Active Locations (1)
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1
Medical Faculty, University of Novi Sad
Novi Sad, Serbia, 21000