Status:

RECRUITING

Identification of Specific Molecular Signatures in Pediatric, Adolescent, and Young Adult Rhabdomyosarcoma Through Spatial Proteome Analysis Using Mass Spectrometry

Lead Sponsor:

Lille University

Collaborating Sponsors:

Centre Oscar Lambret, Lille, France

Conditions:

Rhabdomyosarcoma

Eligibility:

All Genders

Up to 25 years

Brief Summary

This non-interventional study aims to develop spatial proteomics for analyzing small FFPE tumor samples in rhabdomyosarcoma. It will identify molecular signatures linked to tumor regions, subtypes, su...

Detailed Description

This is a non-interventional, monocentric, retrospective cohort study aimed at developing a spatial proteomics analysis method for small tumor samples (FFPE) to precisely characterize proteins at the ...

Eligibility Criteria

Inclusion

  • Age between 0 and 25 years at the time of initial diagnosis
  • Diagnosis of rhabdomyosarcoma confirmed histologically
  • Care at the Oscar Lambret Center between January 2005 and November 2024
  • No objection to the re-use of data and biological samples collected as part of care for research activities.

Exclusion

  • Unavailability of biological sample in FFPE from biopsy and/or surgical specimen for diagnosis at Centre Oscar Lambret;
  • Patient under guardianship or trusteeship.

Key Trial Info

Start Date :

March 13 2025

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

February 28 2026

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT06924463

Start Date

March 13 2025

End Date

February 28 2026

Last Update

April 11 2025

Active Locations (1)

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Oscar Lambret Center

Lille, Nord, France, 59000