Status:

RECRUITING

Efficacy and Safety of Secukinumab in Conjunction With Surgery in Moderate to Severe Hidradenitis Suppurativa

Lead Sponsor:

Peking Union Medical College

Conditions:

Hidradenitis Suppurativa (HS)

Hidradenitis Suppurativa (Acne Inversa)

Eligibility:

All Genders

Up to 80 years

Brief Summary

This study aims to retrospectively analyze the efficacy and safety of secukinumab combined with surgery in treating moderate to severe HS in real-world clinical practice, providing clinical practioner...

Detailed Description

Hidradenitis suppurativa (HS) is a chronic, recurrent, and disabling inflammatory disease that occurs in apocrine distribution sites such as the axilla, groin, and perianal region with a worldwide pre...

Eligibility Criteria

Inclusion

  • Patients aged 18 to 80 years old with moderate-severe (Hurley II-III) HS
  • The diagnosis of HS was confirmed by histopathological examination in the Department of Pathology of our hospital
  • Patients with HS who received secukinumab combined with surgery in the Department of Dermatologic Surgery of our hospital
  • Patients with complete clinical data followed up for at least 1 year

Exclusion

  • Patients lost to follow-up
  • Patients with less than one year of follow-up
  • Patients who received additional adjuvant therapy during the follow-up period

Key Trial Info

Start Date :

January 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 21 2025

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT06926192

Start Date

January 1 2020

End Date

June 21 2025

Last Update

April 16 2025

Active Locations (1)

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1

Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Science and Peking Union Medical College

Nanjing, Jiangsu, China, 210042